Men with erectile dysfunction (ED) may be treated with the drug Fildena 200mg. The medication's active component, sildenafil citrate, is categorized as a phosphodiesterase type 5 (PDE5) inhibitor. The medication works by blocking the PDE5 enzyme, which breaks down cyclic guanosine monophosphate (cGMP) in the penis' smooth muscle cells.
Normal sexual arousal causes the nitric oxide to be released, which in turn activates the guanylate cyclase enzyme, raising the levels of cGMP. As a result, the smooth muscles in the penile arteries become more relaxed, increasing the amount of blood that reaches the erectile tissue. By blocking PDE5, Fildena 200mg contributes to the maintenance of elevated cGMP levels, which in turn prolongs muscle relaxation and enhances blood flow to the penis.